张阳，博士，教授，博士生导师
e-mail: yang.zhang@scu.edu.cn
地址：437必赢会员中心A804室
学术兼职：
生物资源与生态环境教育部重点实验室（四川大学）主任
中国植物学会植物整合组学专业委员会 副主任
中国植物生理与植物分子生物学学会植物代谢专业委员会 副主任
四川省细胞生物学会植物学专委会 主任
Journal of Integrative Plant Biology 编委
aBIOTECH编委
Synthetic and Systems Biotechnology编委
Science China Life Sciences 青年编委
学习及工作经历：
2005.09-2009.06 四川大学，生物技术，学士
2009.10-2014.07 英国约翰英纳斯中心/东安格利亚大学，生物学，博士
2014.08-2015.12 英国约翰英纳斯中心，博士后
2016.03-2018.08 437必赢会员中心，特聘研究员，博导
2018.09-2023.08 437必赢会员中心，研究员，博导
2023.09-至今 437必赢会员中心，教授，博导
学术荣誉：
四川大学“先进集体”（2025）
中国植物生理与植物分子生物学学会“卫志明青年创新奖”（2024）
四川省学术与技术带头人（2021）
四川省教科文卫工会“劳模（职工技能人才）创新工作室（2018）
四川省特聘专家（2017）
研究方向：
本实验室致力于植物代谢的研究，主要关注以下几个方面：
解析重要植物代谢产物的合成途径，发现酶的新功能
解析植物代谢网络的调控机制，鉴定新的代谢调控因子
开展代谢工程及合成生物学研究，创制营养强化新种质
近年来作为负责人主持的代表性科研项目：
四川省自然科学基金创新研究群体，2023NSFSC1991，2023-2025
科技部重点研发青年项目，2022YFF1001900，2022-2027
国家自然科学基金面上项目，32170266，2022-2025
国家自然科学基金青年项目，31701255，2018-2020
国家自然科学基金面上项目，31670352，2017-2020
近年来专利授权情况：
1.付饶; 项玉婷; 张阳 细胞色素P450单加氧酶LsDHLS的应用，2025-04-18，中国发明专利，ZL 2024 1 0221084.5
2.张阳；张子昕；张昕；张静；江文倩 SlPIF4作为负调控因子在提升番茄果实褪黑素含量中的应用，2024-04-09，中国发明专利，ZL 2022 1 1391519.8
3.张阳；魏硕；付饶；多酚氧化酶的应用及合成黄酮的方法，2023-06-16，中国发明专利，ZL 2021 1 0448995.8
4.张阳；袁勇；吴钰；任思彦；番茄SlWRKY35基因在提高番茄类胡萝卜素类化合物或/和叶绿素含量中的应用，2023-04-28，中国发明专利，ZL 2021 1 0342002.9
5.张阳；李彦；周璐；付饶；参与调控番茄甾体生物碱合成转录因子的应用，2021-02-19，中国发明专利，ZL 2019 1 0847193.7
近年来代表性通讯作者工作
Zixin Zhang*, Jing Zhang*, Yi Wang, Yuting Chen, Qian Hu, Xin Zhang, Wen Li, Yiren Xiao, Ke Zhou, Yanlin Lai, Dan Su, Evangelos Tatsis, Gaofeng Liu, Mingchun Liu, Zhenhui Zhong, Yang Zhang#. (2026) Light regulates tomato fruit metabolome via SlDML2-mediated global DNA demethylation. Journal of Integrative Plant Biology https://doi.org/10.1111/jipb.70066
Jiayi Chen, Mingchun Liu, Yang Zhang#, Feng Bai# (2026) Dissecting the biosynthesis, regulation and metabolic engineering of steroidal glycoalkaloids in tomato. Journal of Integrative Plant Biology doi: 10.1111/jipb.70077.
Yuting Xiang, Tingting Liang, Ruixi Yang, Hsihua Wang, Alisdair R. Fernie, Yang Zhang#, Rao Fu# (2025) Functional divergence of tandem duplicate SCPL acyltransferase genes reveals convergent 4 evolution of chicoric acid biosynthesis. Science Advances 11: eady8282
Yuting Xiang, Shuxin Zheng, Hsihua Wang, Bang Chen, Rao Fu, Tao Huang, Li Zhang, Bo Song, Yuejian Li, Qichang Yang, Xiao Yang#, Yang Zhang#. (2025) Multi-omics study reveals a light-dependent regulatory network of flavonoid biosynthesis in lettuce (Lactuca sativa L.). SCIENCE CHINA Life Sciences 68, 2442–2455
Sanming Zhu, Rao Fu, Cathie Martin#, Qing Zhao#, Yang Zhang# (2025) Recent advances in biosynthesis, regulation, and metabolic engineering of flavonoids. Plant Physiology 199 (1): kiaf356
Jingjin Wang, Zikun Wang, Hsihua Wang, Pai, M., Tingting Li, Zhang, H., Bengui Ye, Ling Tang, Rao Fu#, Yang Zhang# (2025) UDP-glucosyltransferases from UGT73 family catalyze 3-O-glucosylation of isosteroidal and steroidal alkaloids in Fritillaria unibracteata var. wabuensis. The Plant Journal 121:e70042
Shengjie You, Yu Wu, Wen Li, Xiaofeng Liu, Qinlan Tang, Fengkun Huang, Yan Li, Hsihua Wang, Mingchun Liu, Yang Zhang# (2024) SlERF.G3-Like mediates a hierarchical transcriptional cascade to regulate ripening and metabolic changes in tomato fruit. Plant Biotechnology Journal 22(1):165-180
Zixin Zhang, Xin Zhang, Yuting Chen, Wenqian Jiang, Jing Zhang, Jiayu Wang, Yanjun Wu, Shouchuan Wang, Xiao Yang, Mingchun Liu, Yang Zhang# (2023) Understanding the mechanism of red light induced melatonin biosynthesis facilitates the engineering of melatonin-enriched tomatoes. Nature Communications 14:5525
Peng Shu*, Zixin Zhang*, Yi Wu, Yuan Chen, Kunyan Li, Heng Deng, Jing Zhang, Xin Zhang, Jiayu Wang, Zhibin Liu, Yue Xie, Kui Du Mingzhang Li, Mondher Bouzayen, Yiguo Hong, Yang Zhang#, Mingchun Liu# (2023) A comprehensive metabolic map reveals major quality regulations in red-flesh kiwifruit (Actinidia chinensis). New Phytologist 238(5):2064-2079
Yong Yuan, Siyan Ren, Xiaofeng Liu, Liyan Su, Yu Wu, Wen Zhang, Yan Li, Yidan Jiang, Hsihua Wang, Rao Fu, Mondher Bouzayen, Mingchun Liu, Yang Zhang# (2022) SlWRKY35 positively regulates carotenoid biosynthesis by activating the MEP pathway in tomato fruit. New Phytologist 234(1):164-178
Rao Fu#*, Pingyu Zhang*, Ge Jin, Shuo Wei, Jiang Chen, Jin Pei, Yang Zhang# (2022) Substrate promiscuity of acyltransferases contributes to the diversity of hydroxycinnamic acid derivatives in purple coneflower. The Plant Journal 110: 802–813
Shuo Wei, Yuting Xiang, Yang Zhang#, Rao Fu# (2022) The unexpected flavone synthase-like activity of polyphenol oxidase in tomato. Food Chemistry 377:131958
Jing Zhang*, Xiao Yang*, Xin Zhang*, Li Zhang, Zixin Zhang#, Yang Zhang #, Qichang Yang# (2022) Linking environmental signals to plant metabolism: The combination of field trials and environment simulators. Molecular Plant 15:213-215
Yanjun Wu*, Yong Yuan*#, Wenqian Jiang, Xin Zhang, Siyan Ren, Hsihua Wang, Xiaolan Zhang, Yang Zhang# (2022) Enrichment of health-promoting lutein and zeaxanthin in tomato fruit through metabolic engineering. Synthetic and Systems Biotechnology 7:1159-1166
Siyan Ren*, Yong Yuan*, Hsihua Wang, Yang Zhang# (2022) G2-LIKE CAROTENOID REGULATOR (SlGCR) is a positive regulator of lutein biosynthesis in tomato. aBIOTECH 3:267–280
Rao Fu*, Pingyu Zhang*, Ge Jin, Lianglei Wang, Shiqian Qi, Yang Cao, Cathie Martin, Yang Zhang# (2021) Versatility in acyltransferase activity completes chicoric acid biosynthesis in purple coneflower. Nature Communications 12: 1563
Rao Fu*, Jie Li*, Huatao Yu*, Yang Zhang#, Zhihong Xu#, Cathie Martin# (2021) The Yin and Yang of traditional Chinese and Western medicine. Medicinal Research Reviews 41(6):3182-3200
Yan Li*, Yang Chen*, Shengjie You*, Lu Zhou*, Heng Deng, Ya Chen, Saleh Alseekh, Yong Yuan, Rao Fu, Zixin Zhang, Dan Su, Alisdair R. Fernie, Mondher Bouzayen, Tao Ma, Mingchun Liu#, Yang Zhang# (2020) MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle. Molecular Plant 13:1203-1218
Zixin Zhang and Yang Zhang#. (2020) A Transcriptional Network Makes Normal Tomato Fruit Not Purple. Molecular Plant 13: 11–13
Shiyu Ying*, Min Su*, Yu Wu, Lu Zhou, Rao Fu, Yan Li, Hao Guo, Jie Luo, Shouchuang Wang#, Yang Zhang# (2020) Trichome regulator SlMIXTA‐like directly manipulates primary metabolism in tomato fruit. Plant Biotechnology Journal 18:354-363
论文发表详细情况请见：https://scholar.google.com/citations?user=2zk_C0oAAAAJ&hl=en
